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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24C
All Species:
28.48
Human Site:
S543
Identified Species:
44.76
UniProt:
P53992
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53992
NP_004913.2
1094
118325
S543
R
E
G
G
A
E
E
S
A
I
R
V
G
F
V
Chimpanzee
Pan troglodytes
XP_001145058
1094
118246
S543
R
E
G
G
A
E
E
S
A
I
R
V
G
F
V
Rhesus Macaque
Macaca mulatta
XP_001104565
998
107625
R493
H
L
D
H
T
G
K
R
V
D
A
Y
D
R
P
Dog
Lupus familis
XP_850963
1096
118584
S545
R
E
G
G
T
E
E
S
A
I
R
V
G
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
G542
G
N
T
R
T
K
I
G
F
I
T
F
D
S
T
Rat
Rattus norvegicus
NP_001102926
1095
118506
S544
R
E
G
G
A
E
E
S
A
I
R
V
G
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513100
1030
112379
L524
C
E
V
F
V
P
L
L
D
G
F
L
V
N
Y
Chicken
Gallus gallus
XP_421617
1147
124543
S596
R
E
G
N
M
E
E
S
A
I
R
V
G
F
V
Frog
Xenopus laevis
NP_001087832
1126
123503
S575
R
E
S
N
M
E
E
S
V
I
R
V
G
F
V
Zebra Danio
Brachydanio rerio
XP_700597
1315
142554
H742
R
E
Y
V
C
F
W
H
L
Q
P
N
M
M
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392952
1276
140829
T724
I
D
A
G
Q
S
K
T
N
M
K
V
G
F
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783728
1150
123558
S599
K
E
H
G
A
K
E
S
N
I
R
V
G
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M081
1080
116273
G546
E
G
P
R
T
F
V
G
I
A
T
F
D
S
T
Baker's Yeast
Sacchar. cerevisiae
P53953
876
98925
Q371
K
K
I
P
E
I
F
Q
D
T
H
S
S
K
F
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
S445
E
C
R
Q
N
I
E
S
F
L
N
K
L
P
E
Conservation
Percent
Protein Identity:
100
99.5
86.9
94.8
N.A.
26.9
92
N.A.
51.9
75.4
69
59.5
N.A.
N.A.
44.5
N.A.
52.6
Protein Similarity:
100
99.7
87.9
96.1
N.A.
45.8
94.4
N.A.
66.2
82.3
78.1
69
N.A.
N.A.
59.4
N.A.
64.3
P-Site Identity:
100
100
0
93.3
N.A.
6.6
100
N.A.
6.6
86.6
73.3
13.3
N.A.
N.A.
26.6
N.A.
73.3
P-Site Similarity:
100
100
6.6
93.3
N.A.
13.3
100
N.A.
13.3
86.6
73.3
13.3
N.A.
N.A.
66.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
22.4
30
Protein Similarity:
N.A.
N.A.
N.A.
49.3
41.1
47
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
27
0
0
0
34
7
7
0
0
0
0
% A
% Cys:
7
7
0
0
7
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
7
7
0
0
0
0
0
14
7
0
0
20
0
0
% D
% Glu:
14
60
0
0
7
40
54
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
7
0
14
7
0
14
0
7
14
0
54
7
% F
% Gly:
7
7
34
40
0
7
0
14
0
7
0
0
54
0
0
% G
% His:
7
0
7
7
0
0
0
7
0
0
7
0
0
0
0
% H
% Ile:
7
0
7
0
0
14
7
0
7
54
0
0
0
0
7
% I
% Lys:
14
7
0
0
0
14
14
0
0
0
7
7
0
7
0
% K
% Leu:
0
7
0
0
0
0
7
7
7
7
0
7
7
0
0
% L
% Met:
0
0
0
0
14
0
0
0
0
7
0
0
7
7
0
% M
% Asn:
0
7
0
14
7
0
0
0
14
0
7
7
0
7
0
% N
% Pro:
0
0
7
7
0
7
0
0
0
0
7
0
0
7
7
% P
% Gln:
0
0
0
7
7
0
0
7
0
7
0
0
0
0
0
% Q
% Arg:
47
0
7
14
0
0
0
7
0
0
47
0
0
7
0
% R
% Ser:
0
0
7
0
0
7
0
54
0
0
0
7
7
14
0
% S
% Thr:
0
0
7
0
27
0
0
7
0
7
14
0
0
0
14
% T
% Val:
0
0
7
7
7
0
7
0
14
0
0
54
7
0
47
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _